The Big Bus (1976)

Director: James Frawley
Cast: Bob Dishy, John Beck, José Ferrer, Joseph Bologna, Ned Beatty, René Auberjonois, Ruth Gordon, Stockard Channing

Synopsis:

The ultimate disaster film parody. A nuclear-powered bus is making its maiden non-stop trip from New York to Denver. The journey is plagued by disasters due to the machinations of a mysterious group allied with the oil lobby. Will the down-on-his-luck driver, with a reputation for eating his passengers, be able to complete the journey?